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"Freeze My Future"
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Truths and myths of oocyte sensitivity to cryopreservation The mammalian oocyte is especially sensitive to cryopreservation. Because of its size and physiology, it can easily undergo cell death or sub-lethal damage as a consequence of intracellular ice formation, increase in the concentration of solutes, a phenomenon referred to as solution effect, and other undesired effects occurring during the conversion of extracellular water into ice. Reproductive Biomedicine Online, Feb 19, 2007 Cryopreservation of supernumerary oocytes in IVF/ICSI cycles The aim of the present study is to investigate cryopreservation of oocytes in patients refusing embryo cryopreservation for ethical reasons, patients from whom no sperm could be retrieved and patients with enough oocytes to yield a number of fresh and cryopreserved embryos to transfer. Human Reproduction, Feb 1, 2006 Meiotic spindle imaging in human oocytes frozen with a slow freezing procedure involving high sucrose concentration One of the major concerns derived from the cryopreservation of meiotically mature oocytes is possible damage to the cytoskeletal apparatus, and in particular the meiotic spindle. Human Reproduction, Apr 1, 2005 Polscope analysis of meiotic spindle changes in living metaphase II human oocytes during the freezing and thawing procedures The clinical efficacy of the current methods used for cryopreservation of metaphase II human oocytes is low. Meiotic spindle disorders are thought to be largely responsible for this situation. Human Reproduction, Mar 1, 2004 | |||||||||||||||||||||||||||||||||||||||||||||||||
